Research Article

Bacteriological and Antibiotic Resistance Profile of Isolated Organisms of Post-Caesarean Suppuration in the Department of Gynaecology and Obstetrics of Laquintinie Hospital, Douala, Cameroon

Author: Essome H

Introduction: The objective of our study was to identify the bacteria associated with the post-Caesarean surgical site infection, and their antibiotic resistance profile, in the Department of Gynaecology and Obstetrics at Laquintinie Hospital in Douala. Methods: We conducted a cross-sectional and analytical study on the removal of post-caesarean section suppuration at Laquintinie Hospital in Douala. After swabbing the superficial pus and syringe puncture for the deepest pus, the samples were sown on culture media allowing the growth of most of the germs involved in this type of infection. Identification was made using ApiTM galleries (BioMerieux, France), and antibiotic resistance using the Mueller Hinton agar plate method. Results: We had 260 cases of caesareans during the study period. The mean age of the patients was 27.2 ± 0.6 years, the Mean Hospital Stay (MHS) was 9.1 ± 0.4 days. The prevalence of infection was 28.8%, considered to be associated with care in most of cases. The bacteria responsible for these infections were mostly Gram-positive cocci (45%), followed by enterobacteria (32%), and non-fermenting gram-negative bacilli (23%). Staphylococcus aureus was the predominant species with 33% of cases, followed by Pseudomonas aeruginosa 21% and Klebsiella pneumoniae 11%. The bacteria encountered were multi-resistant to the different families of antibiotics tested, with a resistance level varying between 92 and 98% with respect to betalactamines, including for imipenem (47% of resistant strains). Isolated organisms were resistant to aminoglycosides, namely gentamycin and neltimicin at 51.5% and 81.8%, respectively. Conclusion: Post-caesarean infection is a concern at the Maternity of Laquintinie Hospital. Reinforcement of hygiene measures, knowledge of local bacterial ecology and surveillance of antibiotic resistance are necessary to improve the management of these infections