Research Article

Pursuit, Salience, and an Urge to Turn Left: A Review of the Frontal Eye Fields

Author: Geoffrey Adrian Tipper

In 2016 a patient was referred urgently to the regional neurosurgical service with a newly diagnosed primary brain tumour. The patient’s presentation had been both striking and unusual: she had developed a progressive and irresistible urge to turn to the left. This proved to be due to a lesion neatly confined to the right frontal eye field. Its irritative properties were causing an unusual seizure variant manifesting itself in this movement disorder. The patient went on to have a successful craniotomy and remains well two years later. The episode prompted a review of this relatively unknown region of the frontal lobes. This review not only explains the unusual episode but demonstrates widespread implications for many fields of medical practice